Supplementary information:

A Fast Top-Down Method for Constructing Reliable Radiation Hybrid Frameworks

Trond Hellem Bø, Inge Jonassen, Ingvar Eidhammer and Carsten Helgesen

Chromosome

Longest path in MCST

Framework

Agreement vs. GeneMap98

Interval Coverage

Reversed section (Y/N)

Plot vs. GeneMap98

1
379 of 3020 markers
91 markers
1
0.79
N
eps pdf
2
320 of 2212 markers
74 markers
1
0.74
N
eps pdf
3
253 of 1903 markers
67 markers
0.73
0.45
Y
eps pdf
4
210 of 1457 markers
40 markers
0.57
0.37
Y
eps pdf
5
212 of 1412 markers
60 markers
1
0.81
N
eps pdf
6
308 of 1959 markers
90 markers
1
0.81
N
eps pdf
7
235 of 1388 markers
67 markers
0.99
0.71
N
eps pdf
8
185 of 1162 markers
55 markers
1
0.88
N
eps pdf
9
161 of 1014 markers
43 markers
1
0.76
N
eps pdf
10
230 of 1300 markers
61 markers
1
0.82
N
eps pdf
11
181 of 1389 markers
48 markers
0.60
0.35
Y
eps pdf
12
197 of 1425 markers
57 markers
0.75
0.62
Y
eps pdf
13
116 of 682 markers
32 markers
1
0.67
N
eps pdf
14
171 of 954 markers
34 markers
1
0.63
N
eps pdf
15
155 of 981 markers
43 markers
1
0.74
N
eps pdf
16
91 of 971 markers
30 markers
0.57
0.15
Y
eps pdf
17
183 of 1213 markers
37 markers
1
0.50
N
eps pdf
18
140 of 640 markers
36 markers
0.97
0.76
N
eps pdf
19
127 of 921 markers
30 markers
0.47
0.48
Y
eps pdf
20
144 of 782 markers
34 markers
0.97
0.67
N
eps pdf
21
72 of 359 markers
23 markers
1
0.80
N
eps pdf
22
88 of 493 markers
22 markers
0.95
0.81
N
eps pdf