University of Bergen | Faculty of Mathematics and Natural Sciences | Department of Informatics | Visualization Group
Visualization
You are here: Department of Informatics > Visualization Group > Team > Stefan Bruckner > Publications > Kolesar-2014-IIP
 Visualization
 > about
 > team & contact info
 --- >  Stefan Bruckner
 > research
 > publications
 > projects
 > teaching
 > resources
 > network
 > events
 > links

Interactively Illustrating Polymerization using Three-level Model Fusion

Ivan Kolesar, Julius Parulek, Ivan Viola, Stefan Bruckner, Anne-Kristin Stavrum, Helwig Hauser

JOURNAL ARTICLE: BMC Bioinformatics, vol. 15, pp. 345, 2014. DOI: 10.1186/1471-2105-15-345

Abstract

Research in cell biology is steadily contributing new knowledge about many aspects of physiological processes, both with respect to the involved molecular structures as well as their related function. Illustrations of the spatio-temporal development of such processes are not only used in biomedical education, but also can serve scientists as an additional platform for in-silico experiments. Results In this paper, we contribute a new, three-level modeling approach to illustrate physiological processes from the class of polymerization at different time scales. We integrate physical and empirical modeling, according to which approach best suits the different involved levels of detail, and we additionally enable a form of interactive steering, while the process is illustrated. We demonstrate the suitability of our approach in the context of several polymerization processes and report from a first evaluation with domain experts. Conclusion We conclude that our approach provides a new, hybrid modeling approach for illustrating the process of emergence in physiology, embedded in a densely filled environment. Our approach of a complementary fusion of three systems combines the strong points from the different modeling approaches and is capable to bridge different spatial and temporal scales.

Published

BMC Bioinformatics

Documents and Links

  • paper
  • www

Additional Media

  • Click to view
  • Click to view

BibTeX

@ARTICLE{Kolesar-2014-IIP,
  author = {Ivan Kolesar and Julius Parulek and Ivan Viola and Stefan Bruckner
	and Anne-Kristin Stavrum and Helwig Hauser},
  title = {Interactively Illustrating Polymerization using Three-level Model
	Fusion},
  journal = {BMC Bioinformatics},
  year = {2014},
  volume = {15},
  pages = {345},
  month = oct,
  abstract = {Research in cell biology is steadily contributing new knowledge about
	many aspects of physiological processes, both with respect to the
	involved molecular structures as well as their related function.
	Illustrations of the spatio-temporal development of such processes
	are not only used in biomedical education, but also can serve scientists
	as an additional platform for in-silico experiments. Results In this
	paper, we contribute a new, three-level modeling approach to illustrate
	physiological processes from the class of polymerization at different
	time scales. We integrate physical and empirical modeling, according
	to which approach best suits the different involved levels of detail,
	and we additionally enable a form of interactive steering, while
	the process is illustrated. We demonstrate the suitability of our
	approach in the context of several polymerization processes and report
	from a first evaluation with domain experts. Conclusion We conclude
	that our approach provides a new, hybrid modeling approach for illustrating
	the process of emergence in physiology, embedded in a densely filled
	environment. Our approach of a complementary fusion of three systems
	combines the strong points from the different modeling approaches
	and is capable to bridge different spatial and temporal scales.},
  doi = {10.1186/1471-2105-15-345},
  keywords = {biochemical visualization, L-system modeling, multi-agent modeling,
	visualization of physiology, polymerization},
  owner = {bruckner},
  timestamp = {2014.12.29},
  url = {http://www.ii.uib.no/vis/projects/physioillustration/research/interactive-molecular-illustration.html}
}






 Last Modified: Stefan Bruckner, 2017-10-13