@PHDTHESIS {angelelli12thesis,
author = "Paolo Angelelli",
title = "Visual Exploration of Human Physiology: Visualizing Perfusion, Blood Flow and Aging",
school = "Department of Informatics, University of Bergen, Norway",
year = "2012",
month = "Apr",
abstract = "With the technological advancements in medical imaging, it is nowadayspossible to capture in-vivo information related to different human physiologicalsystems. Such data extends the more traditional anatomical scans,but add size, complexity and heterogeneity. In addition, while anatomydata is defined in three-dimensional space, and 3D graphics techniques canbe used to represent it on the screen, physiology information is often moreabstract, and require tailored solutions to be represented in combinationwith their anatomical context.This thesis presents solutions for visualizing selected aspects in threedomains of physiology: blood flow, perfusion and aging. With respect toblood flow, it includes a technique to enhance the side-by-side visualizationof the tubular flow in vessels. This result is achieved with a methodthat generates straightened visualizations of the flow in its context, whichcan be easily aligned and then related to each other. With respect to perfusion,this thesis includes an interactive visual analysis solution that easeand improve the exploration, segmentation and analysis of perfusion dataacquired using contrast-enhanced ultrasound. This result is achieved byusing a statistical framework to extract enhancement information, and aninteractive, correlation-based approach to classify the tissue based on similarity.Finally, with respect to aging, two solutions to help exploring largedata collections of repeated examinations are presented. In one, interactivevisual analysis methods are employed to explore and analyze cohort studydata, while the other focuses on the guided exploration of repeated ultrasoundexaminations. Demonstration case studies are include to exemplifythe utility of the presented work.",
pdf = "pdfs/angelelli12thesis.pdf",
images = "images/angelelli12thesis.png",
thumbnails = "images/angelelli12thesis_thumb.png",
isbn = "978-82-308-2073-5"
}