Publications

Visual analysis of cerebral perfusion data – four interactive approaches and a comparison

S. Oeltze, B. Preim, H. Hauser, J. RØ. rvik, and A. Lundervold

Abstract

Cerebral perfusion data are acquired to characterize the regional blood supply of brain tissue. One of their major diagnostic applications is ischemicstroke assessment. We present a comparison of four interactive approaches to analyzingcerebral perfusion data from ischemic stroke patients which are based on (1) concentration-time curves (CTC) derived from the original data, (2) parameters describing the CTC shape, (3) enhancement trends computed in a statistical analysis, and (4) semi-quantitative perfusion parameters derived via parametric modelling and deconvolution. The comparison is carried out with regard to the involved data pre-processing, the complexity of the interactive analysis and the resulting tissue selections. It is supported by a visual analysis framework that integrates the different approaches. The rich information content in time-dependent 3D perfusion data is both an opportunity for improved diagnosis and a challenge how to optimize the assessment of such rich data. With our comparison we contribute to a discussion between data-near and model-near assessment strategies and their respective opportunities.

S. Oeltze, B. Preim, H. Hauser, J. RØ. rvik, and A. Lundervold, "Visual analysis of cerebral perfusion data – four interactive approaches and a comparison," in Proceedings of the 6th Intern. Symp. on Image and Signal Processing and Analysis (ISPA 2009), 2009, p. 582–589.
[BibTeX]

Cerebral perfusion data are acquired to characterize the regional blood supply of brain tissue. One of their major diagnostic applications is ischemicstroke assessment. We present a comparison of four interactive approaches to analyzingcerebral perfusion data from ischemic stroke patients which are based on (1) concentration-time curves (CTC) derived from the original data, (2) parameters describing the CTC shape, (3) enhancement trends computed in a statistical analysis, and (4) semi-quantitative perfusion parameters derived via parametric modelling and deconvolution. The comparison is carried out with regard to the involved data pre-processing, the complexity of the interactive analysis and the resulting tissue selections. It is supported by a visual analysis framework that integrates the different approaches. The rich information content in time-dependent 3D perfusion data is both an opportunity for improved diagnosis and a challenge how to optimize the assessment of such rich data. With our comparison we contribute to a discussion between data-near and model-near assessment strategies and their respective opportunities.
@INPROCEEDINGS {oeltze09perfusion,
author = "Steffen Oeltze and Bernhard Preim and Helwig Hauser and Jarle R{\O }rvik and Arvid Lundervold",
title = "Visual analysis of cerebral perfusion data -- four interactive approaches and a comparison",
booktitle = "Proceedings of the 6th Intern. Symp. on Image and Signal Processing and Analysis (ISPA 2009)",
year = "2009",
pages = "582--589",
month = "Sept.",
abstract = "Cerebral perfusion data are acquired to characterize the regional blood supply of brain tissue. One of their major diagnostic applications is ischemicstroke assessment. We present a comparison of four interactive approaches to analyzingcerebral perfusion data from ischemic stroke patients which are based on (1) concentration-time curves (CTC) derived from the original data, (2) parameters describing the CTC shape, (3) enhancement trends computed in a statistical analysis, and (4) semi-quantitative perfusion parameters derived via parametric modelling and deconvolution. The comparison is carried out with regard to the involved data pre-processing, the complexity of the interactive analysis and the resulting tissue selections. It is supported by a visual analysis framework that integrates the different approaches. The rich information content in time-dependent 3D perfusion data is both an opportunity for improved diagnosis and a challenge how to optimize the assessment of such rich data. With our comparison we contribute to a discussion between data-near and model-near assessment strategies and their respective opportunities.",
images = "images/oeltze09perfusion1.jpg, images/oeltze09perfusion2.jpg",
thumbnails = "images/oeltze09perfusion1_thumb.jpg, images/oeltze09perfusion2_thumb.jpg"
}
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